Oxamate carbamoyltransferase

oxamate carbamoyltransferase
Identifiers
EC no.2.1.3.5
CAS no.62213-52-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, oxamate carbamoyltransferase (EC 2.1.3.5) is an enzyme that catalyzes the chemical reaction

+
 
 
 
H2PO4
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H2PO4
 
oxaluric acid

The enzyme converts oxamic acid to oxaluric acid, with inorganic phosphate as a byproduct.[1][2]

This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the carboxy- and carbamoyltransferases. The systematic name of this enzyme class is carbamoyl-phosphate:oxamate carbamoyltransferase. This enzyme is also called oxamic transcarbamylase. This enzyme participates in purine metabolism.

References

  1. ^ Enzyme 2.1.3.5 at KEGG Pathway Database.
  2. ^ Bojanowski R, Gaudy E, Valentine RC, Wolfe RS (1964). "Oxamic transcarbamylase of Streptococcus allantoicus". J. Bacteriol. 87 (1): 75–80. doi:10.1128/jb.87.1.75-80.1964. PMC 276964. PMID 14102876.